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American Society of Microbiology ABMM Sample Questions:

1. Which of the following viruses is an enveloped, double-stranded DNA virus known to cause latent infections often reactivated during immunosuppression?

A) Influenza A virus
B) Poliovirus
C) Cytomegalovirus (CMV)
D) Rotavirus

2. A clinical microbiology laboratory is investigating a potential outbreak of a highly contagious respiratory virus. To rapidly screen a large number of nasopharyngeal swabs, the MOST appropriate initial diagnostic test would be:

A) Electron microscopy of the samples.
B) Viral culture on a broad range of cell lines.
C) Rapid antigen detection assay.
D) Whole-genome sequencing of viral RNA.

3. The erm gene in Staphylococcus aureus confers resistance to which class(es) of antibiotics via modification of the ribosomal target site?

A) Fluoroquinolones
B) Macrolides, Lincosamides, and Streptogramin B (MLS<sub>B</sub>)
C) Aminoglycosides
D) Beta-lactams only

4. During the processing of stool specimens for ova and parasite examination, the formalin-ethyl acetate concentration procedure primarily serves to:

A) Stain parasite nuclei for easier identification
B) Selectively culture protozoan trophozoites
C) Preserve parasite morphology and kill bacteria
D) Separate parasites from fecal debris and concentrate them

5. Lyme disease, characterized initially by erythema migrans, is caused by Borrelia burgdorferi. What is the primary arthropod vector responsible for transmitting this spirochete to humans in the Northeastern United States?

A) Pulex irritans (Human flea)
B) Amblyomma americanum (Lone Star tick)
C) Ixodes scapularis (Blacklegged tick)
D) Dermacentor variabilis (American dog tick)

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